According to research ‘Elovanoids,’ bioactive chemical messengers made from omega-3 very long-chain polyunsaturated fatty acids, may prevent the virus from entering cells and protect lung air cells (alveoli). The study was conducted at Louisiana State University Health New Orleans Neuroscience Center of Excellence. Elovanoids (ELVs) were evaluated in petri dish cultures on infected lung tissue from a 78-year-old man.
They discovered that ELVs not only inhibited the SARS-CoV-2 spike protein’s capacity to bind to receptors and enter cells but also induced the creation of protective, anti-inflammatory proteins that protect against lung injury.
ELVs, according to the researchers, reduced the generation of ACE2.
ACE2 is a protein found on the surface of many different types of cells.
On cells, ACE2 receptors operate as locks, and SARS-CoV-2 spike proteins operate as keys that unlock the locks, allowing the virus to enter and multiply quickly.
The SARS-CoV-2 virus is still circulating in many parts of the world, and containing the COVID-19 pandemic will necessitate widespread immunization among the worldwide population. Even though vaccine-induced immunity is critical for obtaining SARS-CoV-2 immunity, several people have recovered from COVID-19.
It’s critical to understand how these people maintain and build viral immunity. The findings show that most people in a group of recovered, mostly mild cases had detectable T and antibody responses to SARS-CoV-2 for nine months after infection, according to the researchers.
“Because SARS-CoV-2 affects the nasal mucosa, GI tract, eye, and neurological system, discovering the protective potential of ELVs broaden the scope of our research beyond the lungs.
Our findings lay the groundwork for therapies aimed at reducing disease risk, progression, and lung protection against Covid-19 and other diseases (including some types of pneumonia) “Dr. Bazan added.
